What is this research about?
Young children admitted to hospital with signs of infection are treated with antibiotics. However, bacteria are increasingly becoming resistant to the antibiotics that are normally used. This may make it harder to recover from their illnesses. In Africa, alternative drugs that work are expensive and may themselves cause the bacteria to become resistant. New alternatives are therefore needed. One drug that might be able to be used as an alternative is Fosfomycin. This drug is used in Europe and America to treat some infections in adults and children. The drug can now be obtained cheaply since it has come off patent. Since it has not been used a lot in this part of the world the risk of bacterial resistance is likely to be low. However, more information about the drug is needed to inform the best dose to use in newborns.